mRNA Is Never Naked, Exploring RBP Target Space & Therapeutic Opportunities

Research11/14/2023 4:00 PM

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mRNA is never caught naked. RNA binding proteins (RBPs), act as vigilant guardians, covering RNA within cells. The role of RBPs is multifaceted, affecting mRNA processing, localization, life-time, and translation, working at steady state or leading to an instantaneous effect on their target mRNA upon stimuli. RBPs constitute an unexplored frontier, specifically implicated in different diseases including cancer, Neurodegeneration, and inflammation. Over the last decade, advancements in this novel target space have brought us to a juncture where the promise of these new therapeutic opportunities is greater than ever. Join our upcoming webinar to gain insights from expert speakers who have made significant advancements in the field of RBPs: -Definition of an RBP – domains and functional activity -Identification of novel RBPs and RBP-RNA interaction using machine learning -Delve into innovative strategies for discovering RBP modulators


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Anima Biotech

Anima Biotech

Anima is a TechBio company at the intersection of mRNA biology and AI. We are advancing the mRNA Lightning platform for the discovery of mRNA drugs and targets. Built from the ground up with over a decade of expertise in mRNA biology, the platform integrates mRNA biology with AI imaging technologies to visualize the entire life cycle of mRNA in cells and decode the mRNA biology underlying a disease. Utilizing millions of images from both healthy and diseased cells, we train disease-specific mRNA image analysis neural networks to recognize a disease signature, an mRNA biology pathway that underlies disease phenotype. Our MOAi technology, the mRNA biology large language model and the Lightning co-pilot work along the process to elucidate the mechanisms of action and molecular targets. Anima’s mRNA Lightning platform is validated by our strategic collaborations.