Nucleus Biologics

Manufacturing cell and gene therapy products is complex and involves multiple challenges, including a unique combination of expensive cell culture solutions and experience. It is crucial to keep the end product in mind from the beginning in order to expedite processes and ensure a seamless scale-up, while reducing costs. Optimizing cell culture media and buffers to fit your process allows you to enhance experimental conditions, improve cell performance, and achieve more reliable and reproducible results in your studies.  In this webinar, our experts will discuss the importance of optimized cell media and buffers using the design of classical media formulations to demonstrate the importance of component selection in the formulation process. Our collaborators at University of Pennsylvania and SK pharmteco will explain how media and buffer design has optimized their processes and improved outcomes. You will learn how cell media and buffers can impact cell growth, viability, and therapeutic efficacy as well as strategies to simplify custom media and buffer design and optimization for all stages of development and manufacturing.  Key Takeaways: • Understand how customized media and buffers can optimize CQAs in C&GT. • Explore real-world case studies demonstrating the impact of customized solutions. • Gain practical insights into improving bioprocess development and consistency. Speakers: Asma Ayari, Ph.D., Director of Research and Development, Nucleus Biologics; John Bowen, Ph.D., Senior Director of Nucleic Acids and Plasmid Operations, SK pharmteco; Roddy O’Connor, Ph.D., Research Assistant Professor, Center for Cellular Immunotherapies, University of Pennsylvania Perelman School of Medicine.